Pacinian neurofibroma

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Pacinian neuroma.

Neural tumors composed of Pacinian corpuscles are rare and have only occasionally been reported in the literature. All such lesions, which have been reported to date, have been benign. One such lesion described here presented as a painful lesion on the right hand in a 17-year-old Omani female. There was history of trap door injury 7 years back involving the wrist, thumb and index finger. The pa...

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Electron Microscopy of the Pacinian Corpuscle

The Pacinian corpuscle has a framework of cytoplasmic lamellae arranged concentrically in the outer zone, and bilaterally in the core. Between these is an intermediate growth zone. The inner core shows an unexpected complexity in that its component lamellae are arranged in two symmetrical groups of nested cytoplasmic sheets. Longitudinal tissue spaces form clefts separating the two groups. The ...

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Solitary neurofibroma

Biopsy of the lesion at scanning power shows laminar hyperkeratosis of the epidermis, slight irregular acanthosis, and a perivascular lymphocytic inflammatory infiltrate in the papillary and superficial reticular dermis (Fig. 3), in the mid reticular dermis there is an unencapsulated, poorly defined neoplasm, consisting of a symmetrically arranged proliferation of wavy spindle cells in fascicle...

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Pelvic Neurofibroma

A 58-year old male presented with a hard lump in lower abdomen extending into pelvis. Clinical examination and computed tomography scan revealed pelvic retroperitoneal mass. Patient underwent exploratory laparotomy - revealing a well encapsulated retroperitoneal mass extending up to coccyx, posterior to the urinary bladder. It had displaced the recto-sigmoid colon and urinary bladder to the rig...

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Mechanisms of Mechanotransduction in the Pacinian Corpuscle

Touch perception is important in most living organisms and extremely sensitive detection systems have evolved to meet this need. Pacinian corpuscles (PCs) are primary mechanoreceptors. In the human, they are found in the skin (where they act as touch receptors), in the joints, in muscles and in many organs (where they act as motion sensors). The purpose of the work described in this thesis is t...

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ژورنال

عنوان ژورنال: Cancer

سال: 1952

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(195203)5:2<297::aid-cncr2820050215>3.0.co;2-3